Citation: Shang Chengxiang, Cai Chao, Zhao Cuixia, Du Yuguo. Synthesis and anti-inflammatory activity of gold-nanoparticle bearing a dermatan sulfate disaccharide analog[J]. Chinese Chemical Letters, ;2018, 29(1): 81-83. doi: 10.1016/j.cclet.2017.06.010 shu

Synthesis and anti-inflammatory activity of gold-nanoparticle bearing a dermatan sulfate disaccharide analog

Shang Chengxiang ^a,b ,
Cai Chao ^a,c ,
Zhao Cuixia ^a,b ,
Du Yuguo ^a,,

a.
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
b.
School of Chemistry and Chemical Engineering, Graduate University of Chinese Academy of Sciences, Beijing 100049, China
c.
Key Lab of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China

Corresponding author: Du Yuguo, duyuguo@rcees.ac.cn
Received Date: 27 March 2017
Revised Date: 23 April 2017
Accepted Date: 2 June 2017
Available Online: 4 January 2017

Figures(3)

A dermatan sulfate (DS) repeating disaccharide analog, α-_L-idopyranosiduronate-(1→3)-2-amino-2-deoxy-4, 6-di-O-sulfo-β-_D-galactopyranoside, has been convergently synthesized and successfully applied to prepare the GAG-functionalized gold glyconanoparticle. This new material exhibited good anti-inflammatory activity which was comparable to that of the drug ibuprofen incarrageenan-induced paw edema in a rat model.
- L-Iduronic acid,
- Gold glyconanoparticles,
- Dermatan sulfate disaccharide,
- Anti-inflammatory,
- Carbohydrates
1. [1]
  R. Elghanian, J.J. Storhoff, R.C. Mucic, R.L. Letsinger, C.A. Mirkin, Science 277(1997) 1078-1081. doi: 10.1126/science.277.5329.1078
2. [2]
  A.C. Temleton, W.P. Wuelfing, A.W. Murray, Acc. Chem. Res. 33(2000) 27-36. doi: 10.1021/ar9602664
3. [3]
  S.D. Brown, P. Nativo, J.A. Smith, et al., J. Am. Chem. Soc.132(2010) 4678-4684. doi: 10.1021/ja908117a
4. [4]
  I. Tokareva, E. Hutter, J. Am. Chem. Soc. 126(2004) 15784-15789. doi: 10.1021/ja046779k
5. [5]
  J. Rojo, V.D. Ìaz, J.M. Fuente, et al., ChemBioChem 5(2004) 291-297. doi: 10.1002/cbic.v5:3
6. [6]
  L. Zhang, G.H. Wei, Y. Du, Carbohydr. Res. 344(2009) 2083-2087. doi: 10.1016/j.carres.2009.06.039
7. [7]
  J.M. Trowbridge, R.L. Gallo, Glycobiology 12(2002) 117R-125R. doi: 10.1093/glycob/cwf066
8. [8]
  R.J. Linhardt, R.E. Hileman, Gen. Pharmac. 26(1995) 443-451. doi: 10.1016/0306-3623(94)00231-B
9. [9]
  S. Boddohi, N. Moore, P.A. Johnson, M.J. Kipper, Biomacromolecules 10(2009) 1402-1409. doi: 10.1021/bm801513e
10. [10]
  M.M. Kemp, A. Kumar, D. Clement, et al., Nanomedicine 4(2009) 421-429. doi: 10.2217/nnm.09.24
11. [11]
  M.M. Kemp, A. Kumar, S. Mousa, et al., Biomacromolecules 10(2009) 589-595. doi: 10.1021/bm801266t
12. [12]
  M. Guerrini, D. Beccati, Z. Shriver, et al., Nat. Biotechnol. 26(2008) 669-675. doi: 10.1038/nbt1407
13. [13]
  K. Rajangam, H.A. Behanna, M.J. Hui, et al., Nano Lett. 6(2006) 2086-2090. doi: 10.1021/nl0613555
14. [14]
  R. Bhattacharya, P. Mukherjee, Z. Xiong, et al., Nano Lett. 4(2004) 2479-2481. doi: 10.1021/nl0483789
15. [15]
  G.J.S. Lohman, D.K. Hunt, J.A. Hogermeier, P.H. Seeberger, J. Org. Chem. 68(2003) 7559-7561. doi: 10.1021/jo0340760
16. [16]
  M. Adinolfi, G. Barone, L. Guariniello, A. Iadonisi, Tetrahedron Lett. 40(1999) 8439-8441. doi: 10.1016/S0040-4039(99)01756-6
17. [17]
  C. Cai, G.H. Wei, Y. Du, Acta Cryst. E 66(2010) o949. doi: 10.1107/S1600536810010895
18. [18]
  R. Autar, A.S. Khan, M. Schad, et al., ChemBioChem 4(2003) 1317-1325. doi: 10.1002/cbic.200300719
19. [19]
  J.L. Paz, R. Ojeda, A.G. Barrientos, S. Penade, M. Martin-Lomas, Tetrahedron:Asymmetry 16(2005) 149-158. doi: 10.1016/j.tetasy.2004.11.066
20. [20]
  C.A. Winter, E.A. Risley, G.W. Nuss, Exp. Biol. Med. 11(1962) 544-547.
21. [21]
  C. Cai, Investigation of synthetic methodologies of some bioactive oligosaccharides and their analogs, PhD thesis, Graduate School of Chinese Academy of Sciences, 2010.
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