Citation: Salehpour Mahboobeh, Azizian Javad, Kefayati Hassan. Clean synthesis of novel spiro[indene-2, 2'-[1, 3, 5]-oxathiazine]-1, 3-diones in water[J]. Chinese Chemical Letters, ;2017, 28(5): 1079-1082. doi: 10.1016/j.cclet.2016.12.036 shu

Clean synthesis of novel spiro[indene-2, 2'-[1, 3, 5]-oxathiazine]-1, 3-diones in water

a.
Department of Chemistry, Science and Research Branch, Islamic Azad University, P. O. Box 19395-1775, Tehran, Iran
b.
Department of Chemistry, Rasht Branch, Islamic Azad University, Rasht, Iran

Corresponding author: Azizian Javad, azizian@srbiau.ac.ir
Received Date: 31 October 2016
Revised Date: 5 December 2016
Accepted Date: 7 December 2016
Available Online: 9 May 2017

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In this work, we have designed an efficient and convenient method for the synthesis of novel spiro[indene-2, 2'-[1, 3, 5]oxathiazine]-1, 3-diones by the one-pot, three component condensation of tetramethyl guanidine, ninhydrin, and isothiocyanates in water. Easy purification, green reaction conditions, easy performance and good yields are some advantages of this procedure.
- Spiro[indene-oxathiazine],
- Tetramethyl guanidine,
- Ninhydrin,
- Oxathiazine
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沈阳化工大学材料科学与工程学院沈阳 110142