Citation: Wang Xiao-Ling, Di Xia-Xia, Shen Tao, Wang Shu-Qi, Wang Xiao-Ning. New phenolic compounds from the leaves of Artocarpus heterophyllus[J]. Chinese Chemical Letters, ;2017, 28(1): 37-40. doi: 10.1016/j.cclet.2016.06.024 shu

New phenolic compounds from the leaves of Artocarpus heterophyllus

a.
The Second Hospital of Shandong University, Jinan 250033, China
b.
Department of Natural Product Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China

Corresponding author: Wang Xiao-Ning, wangxn@sdu.edu.cn
Received Date: 3 May 2016
Revised Date: 26 May 2016
Accepted Date: 12 June 2016
Available Online: 24 January 2016

Figures(2)

One new 2-arylbenzofuran derivative, artocarstilbene B (1), one new benzaldehyde derivative, (E)-3, 5-dihydroxy-4-(3-methylbut-1-enyl) benzaldehyde (2), as well as 18 known compounds (3-20) were obtained from the leaves of Artocarpus heterophyllus. Their structures were elucidated on the basis of extensive spectroscopic techniques including 2D NMR and HR-ESIMS. Many compounds exhibited moderate to weak inhibitory activity against the proliferation of the PC-3, NCI-H460, and A549 cancer cell lines.
- Artocarpus heterophyllus,
- 2-Arylbenzofuran,
- Artocarstilbene B,
- (E)-3, 5-Dihydroxy-4-(3-methylbut-1-enyl) benzaldehyde,
- Cytotoxicity
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沈阳化工大学材料科学与工程学院沈阳 110142