Citation: Hui-Feng Huang, Cai-Juan Zheng, Guang-Ying Chen, Wen-Qing Yin, Xian Huang, Zheng-Rong Mo. Sesquiterpenoids from Curcuma wenyujin dreg and their biological activities[J]. Chinese Chemical Letters, ;2016, 27(10): 1612-1616. doi: 10.1016/j.cclet.2016.03.043 shu

Sesquiterpenoids from Curcuma wenyujin dreg and their biological activities

a.
Key Laboratory of Tropical Medicinal Plant Chemistry, the Ministry of Education of China, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
b.
Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, the Ministry of Education of China, School of Chemistry and Pharmacy, Guangxi Normal University, Guilin 541004, China
c.
Hainan Bikai Pharmaceutical Co., Ltd., Haikou 570216, China

Corresponding author: Guang-Ying Chen, chgying123@163.com Wen-Qing Yin, yinwq0000@aliyun.com
Received Date: 4 January 2016
Revised Date: 1 March 2016
Accepted Date: 4 March 2016
Available Online: 11 October 2016

Figures(3)

Four new sesquiterpenoids, 4,8-dioxo-6β-hydroxyl-7β,11-epoxycarabrane (1), 4,8-dioxo-6β-hydroxyl-7α,11-epoxycarabrane (2), wenyujinins Q and R (3-4), and nine known sesquiterpenoids (5-13) were isolated from the Curcuma wenyujin (C. wenyujin) dreg. Their structures and relative configurations were elucidated using 1D, 2D NMR, and HR-ESI-MS data. All the compounds were isolated for the first time from the C. wenyujin dreg and evaluated for their antibacterial and antifungal activities. Compounds 3, 5-8 exhibited strong broad-spectrum antifungal activities against tested nine pathogenic fungi.
- Curcuma wenyujin dreg,
- Sesquiterpenoids,
- Antibacterial activity,
- Antifungal activity
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1.
沈阳化工大学材料科学与工程学院沈阳 110142