Citation: Zhang De-Wu, Tao Xiao-Yu, Liu Ji-Mei, Chen Ri-Dao, Zhang Min, Fang Xiao-Mei, Yu Li-Yan, Dai Jun-Gui. A new polyketide synthase nonribosomal peptide synthetase hybrid metabolite from plant endophytic fungus Periconia sp.[J]. Chinese Chemical Letters, ;2016, 27(5): 640-642. doi: 10.1016/j.cclet.2016.02.005 shu

A new polyketide synthase nonribosomal peptide synthetase hybrid metabolite from plant endophytic fungus Periconia sp.

Zhang De-Wu ^a,b ,
Tao Xiao-Yu ^a ,
Liu Ji-Mei ^a ,
Chen Ri-Dao ^a ,
Zhang Min ^a ,
Fang Xiao-Mei ^b ,
Yu Li-Yan ^b,, ,
Dai Jun-Gui ^a,,

a.
State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
b.
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

Corresponding author: Yu Li-Yan, yly@cpcc.ac.cn Dai Jun-Gui, jgdai@imm.ac.cn
Received Date: 15 December 2015
Revised Date: 30 December 2015
Accepted Date: 29 January 2016
Available Online: 2 May 2016

Figures(2)

A new polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) hybrid metabolite, named pericoannosin B (1), was isolated from endophytic fungus Periconia sp. F-31 of the medicinal plant Annona muricata. The structure and absolute configuration were elucidated by means of extensive spectroscopic analyses (HRMS, NMR, IR, and CD).
- Endophytic fungus,
- Periconia,
- PKS-NRPS,
- Pericoannosin B
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沈阳化工大学材料科学与工程学院沈阳 110142