Citation: Elham Tabrizian, Ali Amoozadeh, Salman Rahmani, Elham Imanifar, Saeede Azhari, Masoumeh Malmir. One-pot, solvent-free and efficient synthesis of 2,4,6-triarylpyridines catalyzed by nano-titania-supported sulfonic acid as a novel heterogeneous nanocatalyst[J]. Chinese Chemical Letters, ;2015, 26(10): 1278-1282. doi: 10.1016/j.cclet.2015.06.013 shu

One-pot, solvent-free and efficient synthesis of 2,4,6-triarylpyridines catalyzed by nano-titania-supported sulfonic acid as a novel heterogeneous nanocatalyst

1.
Department of Organic Chemistry, Faculty of Chemistry, Semnan University, Semnan 35131-19111, Iran

Corresponding author: Ali Amoozadeh,
Received Date: 26 February 2015
Available Online: 8 June 2015
Fund Project:

Nano titania-supported sulfonic acid (n-TSA) has found to be a highly efficient, eco-friendly and recyclable heterogeneous nanocatalyst for the solvent-free synthesis of 2, 4, 6-triarylpyridines through one-pot three-component reaction of acetophenones, aryl aldehydes and ammonium acetate. This reported method illustrates several advantages such as environmental friendliness reaction conditions, simplicity, short reaction time, easy work up, reusability of catalyst and high yields of the products. One new compound is reported too. Furthermore, the catalyst could be recycled after a simple work-up, and reused at least six times without substantial reduction in its catalytic activity.
- Nano-titania-supported sulfonic acid,
- Multicomponent reaction,
- 2,4,6-Triarylpyridines,
- Solvent free,
- Heterogeneous nanocatalyst
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沈阳化工大学材料科学与工程学院沈阳 110142