Citation: Sirigireddy Sudharsan Reddy, Bhoomireddy Rajendra Prasad Reddy, Peddiahgari Vasu Govardhana Reddy. Propylphosphonic anhydride (T3P^®) catalyzed one-pot synthesis of α-aminonitriles[J]. Chinese Chemical Letters, ;2015, 26(6): 739-743. doi: 10.1016/j.cclet.2015.03.021 shu

Propylphosphonic anhydride (T3P^®) catalyzed one-pot synthesis of α-aminonitriles

1.
Department of Chemistry, Yogi Vemana University, Kadapa 516003, Andhra Pradesh, India

Corresponding author: Peddiahgari Vasu Govardhana Reddy,
Received Date: 30 November 2014
Available Online: 5 February 2015

The Strecker reaction was performed via a one-pot three component condensation of hetero aromatic/aromatic aldehydes, secondary amines and trimetylsilyl cyanide in the presence of propylphosphonic anhydride (T3P^®) to accomplish the corresponding α-aminonitriles. The main advantages of this method are very short reaction time and excellent yields.
- Strecker reaction,
- α-Aminonitriles,
- Propylphosphonic anhydride,
- 5-Fluoro-3-methyl-2-carbaldehyde
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Propylphosphonic anhydride (T3P®) catalyzed one-pot synthesis of α-aminonitriles

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通讯作者: 陈斌, bchen63@163.com

Propylphosphonic anhydride (T3P^®) catalyzed one-pot synthesis of α-aminonitriles