Citation: Akbar Mobinikhaledi, Hassan Moghanian, Samira Pakdel. Microwave-assisted effi cient synthesis of azlactone derivatives using 2-aminopyridine-functionalized sphere SiO₂ nanoparticles as a reusable heterogeneous catalyst[J]. Chinese Chemical Letters, ;2015, 26(5): 557-563. doi: 10.1016/j.cclet.2014.12.007 shu

Microwave-assisted effi cient synthesis of azlactone derivatives using 2-aminopyridine-functionalized sphere SiO₂ nanoparticles as a reusable heterogeneous catalyst

1.
a Department of Chemistry, Faculty of Science, Arak University, Arak 38156-8-8349, Iran;
2.
b Department of Chemistry, Dezful Branch, Islamic Azad University, Dezful, Iran

Corresponding author: Hassan Moghanian,
Received Date: 10 January 2014
Available Online: 24 November 2014

In the present work, the highly efficient Erlenmeyer synthesis of azlactones catalyzed by 2- aminopyridine, supported on nano-sphere SiO₂ is reported. First, the silica nanoparticles were modified with triethoxysilylpropyl chloride and then 2-aminopyridine was attached to the support via covalent linkages. This new heterogenized catalyst was used for efficient microwave-assisted synthesis of azlactone derivatives with Ac₂O as a condensing agent under solvent-free conditions. The present method offers advantages including high yields, short reaction times and simple work-up. Also, the catalyst can be easily recycled and reused several times, which makes this method attractive, economic and environmentally-benign.
- Nano-sphere silica,
- Azlactone,
- Heterogeneous catalyst,
- Erlenmeyer synthesis,
- Microwave irradiation
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Microwave-assisted effi cient synthesis of azlactone derivatives using 2-aminopyridine-functionalized sphere SiO2 nanoparticles as a reusable heterogeneous catalyst

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通讯作者: 陈斌, bchen63@163.com

Microwave-assisted effi cient synthesis of azlactone derivatives using 2-aminopyridine-functionalized sphere SiO₂ nanoparticles as a reusable heterogeneous catalyst