Citation: Mahnaz Farahi, Bahador Karami, Iman Sedighimehr, Hamideh Mohamadi Tanuraghaj. An environmentally friendly synthesis of 1,4-dihydropyrano [2,3-c]pyrazole derivatives catalyzed by tungstate sulfuric acid[J]. Chinese Chemical Letters, ;2014, 25(12): 1580-1582. doi: 10.1016/j.cclet.2014.07.012 shu

An environmentally friendly synthesis of 1,4-dihydropyrano [2,3-c]pyrazole derivatives catalyzed by tungstate sulfuric acid

1.
Department of Chemistry, Yasouj University, Yasouj 75918-74831, Iran

Corresponding author: Bahador Karami,
Received Date: 27 May 2014
Available Online: 25 June 2014

An efficient three-component synthesis of 6-amino-4-aryl-5-cyano-3-methyl-1-phenyl-1,4-dihydropyrano[2,3-c]pyrazoles via a reaction between 3-methyl-1-phenyl-2-pyrazolin-5-one, aromatic aldehydes and malononitrile using tungstate sulfuric acid as a catalyst was described. Mild conditions, good to excellent yields, easily available catalyst and easy work-up are the key features of this method.
- 6-Amino-4-aryl-5-cyano-3-methyl-1-,
- phenyl-1,4-dihydropyrano[2,3-c]pyrazoles,
- 3-Methyl-1-phenyl-2-pyrazolin-5-one,
- Aromatic aldehyde,
- Malononitrile,
- Tungstate sulfuric acid
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沈阳化工大学材料科学与工程学院沈阳 110142