Citation: Moona Mohsenimehr, Manouchehr Mamaghani, Farhad Shirini, Mehdi Sheykhan, Fatemeh Azimian Moghaddam. One-pot synthesis of novel pyrido[2,3-d]pyrimidines using HAp-encapsulated-γ-Fe₂O₃ supported sulfonic acid nanocatalyst under solvent-free conditions[J]. Chinese Chemical Letters, ;2014, 25(10): 1387-1391. doi: 10.1016/j.cclet.2014.04.025 shu

One-pot synthesis of novel pyrido[2,3-d]pyrimidines using HAp-encapsulated-γ-Fe₂O₃ supported sulfonic acid nanocatalyst under solvent-free conditions

a Department of Chemistry, Faculty of Sciences, University of Guilan, P.
a Department of Chemistry, Faculty of Sciences, University of Guilan, P.O. Box 41335-1914, Rasht, Iran;
2.
b Department of Chemistry, Islamic Azad University, Rasht Branch, Iran

Corresponding author: Manouchehr Mamaghani,
Received Date: 21 February 2014
Available Online: 4 April 2014

Novel pyrido[2,3-d]pyrimidine derivatives were synthesized through a one-pot three-component approach using HAp-encapsulated-γ-Fe₂O₃ [γ-Fe₂O₃@HAp-SO₃H] catalyzed condensation of 6-amino-2-(methylthio or ethylthio)pyrimidin-4(3H)-one, Meldrum's acid and aryl aldehydes at 60℃ and under solvent-free conditions. In this protocol the use of nanocatalyst provided a green, useful and rapid method to generate the products in short reaction times and excellent yields (88%-94%).
- Pyrido[2,3-d]pyrimidines,
- Three-component,
- One-pot,
- [γ-Fe₂O₃@HAp-SO₃H],
- Nanocatalyst
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沈阳化工大学材料科学与工程学院沈阳 110142

One-pot synthesis of novel pyrido[2,3-d]pyrimidines using HAp-encapsulated-γ-Fe2O3 supported sulfonic acid nanocatalyst under solvent-free conditions

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通讯作者: 陈斌, bchen63@163.com

One-pot synthesis of novel pyrido[2,3-d]pyrimidines using HAp-encapsulated-γ-Fe₂O₃ supported sulfonic acid nanocatalyst under solvent-free conditions