Citation: Xiao-Lan Li, Dong-Ling Meng, Jiao Zhao, Ya-Ling Yang. Determination of synthetic phenolic antioxidants in essence perfume by high performance liquid chromatography with vortex-assisted, cloud-point extraction using AEO-9[J]. Chinese Chemical Letters, ;2014, 25(8): 1198-1202. doi: 10.1016/j.cclet.2014.03.005 shu

Determination of synthetic phenolic antioxidants in essence perfume by high performance liquid chromatography with vortex-assisted, cloud-point extraction using AEO-9

a Technology Centre of China Tobacco Guangxi Industrial Co.
a Technology Centre of China Tobacco Guangxi Industrial Co., Ltd., Nanning 530001, China;
2.
b College of Life Science and Technology, Kunming University of Science and Technology, Kunming 650105, China

Corresponding author: Ya-Ling Yang,
Received Date: 25 November 2013
Available Online: 26 February 2014

This study aimed to establish a rapid analytical method to determine antioxidants in essence. A simple, efficient and practical, vortex-assisted, cloud-point extraction (VACPE) procedure is proposed for extracting and pre-concentrating four different of synthetic phenolic antioxidants (SPAs), propyl gallate (PG), tert-butylhydroquinone (TBHQ), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) in essence prior to high performance liquid chromatography (HPLC) analysis. The non-ionic surfactant, fatty alcohol polyoxyethylene ether-9 (AEO-9), was used as extractant and vortex-mixing was utilized to reduce extraction time and improve extraction efficiency. The effective parameters of the extraction process, such as volume of extraction solvent, pH, vortex-mixing time, equilibration temperature and time, were optimized. Under the optimum conditions, the linear range of PG, TBHQ, BHA and BHT was 8.0-800 ng/mL. All correlation coefficients of the calibration curves were higher than 0.996 and relative standard deviations (RSD, n=5) were 2.36%-5.46%. The proposed method was successfully applied to the extraction and determination of antioxidants in essence samples with satisfactory relative recoveries of 89.4%-103.5%. The results confirmed the SPAs of essence could be effectively monitored by this method and also established good reference criteria for essence.
- Vortex-assisted cloud-point extraction,
- AEO-9,
- Antioxidant,
- High performance liquid chromatography,
- Essence
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