Citation: Bin Wang, Zeng Li, Xiao Ning Wang, Jia Heng Tan, Lian Quan Gu, Zhi Shu Huang. A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones[J]. Chinese Chemical Letters, ;2011, 22(8): 951-953. doi: 10.1016/j.cclet.2011.01.034 shu

A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones

Bin Wang ^a,b,a, ,
Zeng Li ^a,a ,
Xiao Ning Wang ^a ,
Jia Heng Tan ^a ,
Lian Quan Gu ^a ,
Zhi Shu Huang ^a

a School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China;
b Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, China

Received Date: 3 November 2010

Fund Project: We thank the Natural Science Foundation of China (Nos. U0832005, 90813011, 20772159, 30801436), the Ministry of Education of the People's Republic of China (No. 200805581163), the Guangdong Natural Science Foundation (No. 8451008901000214), and the Science Foundation of Guangzhou (No. 2009A1-E011-6) for financial support of this study.

A new approach to the facile synthesis of 2-substituted-quinazolin-4(3H)-ones and its derivatives using the condensation reaction of substituted 2-aminobenzamide and orthoesters is reported.
- Quinazolin-4(3H)-ones,
- Synthesis,
- Aminobenzamide,
- Orthoester
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