Citation: Seyed Mohammad Vahdat, Samad Khaksar, Maryam Khavarpour. Oxalic acid as a simple and efficient organocatalyst for three-component synthesis of α-amino nitriles[J]. Chinese Chemical Letters, ;2011, 22(5): 543-546. doi: 10.1016/j.cclet.2010.12.002 shu

Oxalic acid as a simple and efficient organocatalyst for three-component synthesis of α-amino nitriles

a Chemistry Department, Islamic Azad University, Ayatollah Amoli Branch, P.O.Box 678, Amol, Iran;
b Chemical Engineering Department, Islamic Azad University, Ayatollah Amoli Branch, P.O.Box 678, Amol, Iran

Received Date: 30 August 2010

A simple, efficient, and general method has been developed for the synthesis of α-amino nitriles.Oxalic acid as a Brønsted acid promotes the addition of TMSCN to various imines (generated in situ).
- Oxalic acid,
- TMSCN,
- Brønsted acid,
- α-Amino nitriles
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