Citation: Qin Yang, Zheng Lan Yin, Ban Lai Ouyang, Yi Yuan Peng. Pyridinium tribromide catalyzed condensation of indoles and aldehydes to form bisindolylalkanes[J]. Chinese Chemical Letters, ;2011, 22(5): 515-518. doi: 10.1016/j.cclet.2010.11.026 shu

Pyridinium tribromide catalyzed condensation of indoles and aldehydes to form bisindolylalkanes

a Key Laboratory of Green Chemistry, Jiangxi Province and College of Chemistry, Jiangxi Normal University, Nanchang 330022, China;
b Key Laboratory of Small Fuctional Organic Molecule, Ministry of Education and College of Life Science, Jiangxi Normal University, Nanchang 330022, China

Received Date: 9 July 2010

Fund Project: We are grateful to the National Natural Science Foundation of China (Nos.20862009 and 20962010)the National Natural Science Foundation of Jiangxi Province(No.2008GQH0026)and the Science Foundation of Education Department of Jiangxi Province (No.GJJ10386) for their financial support

An efficient synthetic method for bis (indol-3-yl) alkane derivatives has been developed.In the presence of 5 mol% of pyridinium tribromide (PTB), the condensation of indoles and aldehydes proceeded smoothly under mild conditions, giving rise to the corresponding bis (indol-3-yl) alkanes in good to excellent yields.
- Pyridinium tribromide,
- Indole,
- Aldehyde,
- Bis(indol-3-yl)alkane
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