Citation: Shen Yi Shi, Ai Guo Kong, Xin Hua Zhao, Han Ming Ding, Fan Yang, Yong Kui Shan. Nucleophilic substitution of hydrogen in naphthalene by chloride (Cl^-) in ionic liquids[J]. Chinese Chemical Letters, ;2011, 22(2): 147-150. doi: 10.1016/j.cclet.2010.09.021 shu

Nucleophilic substitution of hydrogen in naphthalene by chloride (Cl^-) in ionic liquids

Department of Chemistry, East China Normal University, Shanghai 200062, China

Received Date: 22 July 2010

Fund Project: We thank the key project of Shanghai Science and Technology Committee (Nos. 05JC14070, 06DZ05025, 08JC1408600) for financial supports.

Nucleophilic aromatic substitution of hydrogen in non-activated aromatic ring, a very rare phenomenon in organic chemistry, is found in ionic liquids containing Cl^-as anion under mild reaction conditions. The reaction may be carried out by the addition of the halogen-bonding adduct (Br₂Cl^-) as nucleophile to aromatic ring carbon atom, leading to the formation of the nucleophilic substitution product.
- Ionic liquid,
- Aromatic compound,
- Naphthalene,
- Nucleophilic reaction,
- Halogen bonding
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