Citation: Parvin Kumar, Ashwani Kumar. An expeditious synthesis of isoxazoline using cetyltrimethylammonium cerium nitrate:A phase transferring oxidative 1,3-dipolar cycloaddition[J]. Chinese Chemical Letters, ;2010, 21(11): 1287-1290. doi: 10.1016/j.cclet.2010.05.015 shu

An expeditious synthesis of isoxazoline using cetyltrimethylammonium cerium nitrate:A phase transferring oxidative 1,3-dipolar cycloaddition

Parvin Kumar ^a, ,
Ashwani Kumar ^b

a Department of Chemistry, Guru Nanak Khalsa P G College, Yamuna Nagar, Haryana 135001, India;
b Drug Discovery and Research Laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology, Hissar, Haryana 125001, India

Received Date: 8 March 2010

An expeditious and effective method for synthesis of isoxazoline from aldoximes and activated alkenes using cetyltrimethy-lammonium cerium nitrate at room temperature is described. Reaction was completed within short time period in high yields at room temperature.
- Cetyltrimethylammonium cerium nitrate,
- Isoxazoline,
- Oxime,
- Activated alkene,
- 1,3-Dipolar addition
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