Citation:
Guang Wei Wu, Xiao Jun Li, Yi Gao, Yuan Jia, Jin Ming Gao. New polyhydroxylated metabolite derived from biotransformation of diosgenin by the white-rot fungus Coriolus versicolor[J]. Chinese Chemical Letters,
;2010, 21(4): 446-448.
doi:
10.1016/j.cclet.2009.11.018
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Microbial transformation of diosgenin(1)was carried out with the white-rot fungus,Coriolus versicolor.A new polyhydroxyl metabolite,(25R)-spirost-5-ene-3β,7β,21-triol(2),was obtained as a result of hydroxylation.Its structure was elucidated on the basis of 1D and 2D NMR as well as HR-ESI-MS spectroscopic analysis.
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