Citation: Xin De Tang, Xiao Chao Liang, Nian Feng Han. Y-shaped block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) synthesized by ATRP[J]. Chinese Chemical Letters, ;2009, 20(11): 1353-1356. doi: 10.1016/j.cclet.2009.06.007 shu

Y-shaped block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) synthesized by ATRP

a Institute of New Materials, Shandong Jiaotong University, Ji'nan 250023, China;
b College of Chemistry & Molecular Engineering, Peking University, Beijing 100871, China

Received Date: 19 March 2009

Fund Project: and the Science Research Fund of Shandong Jiaotong University of China (No. Z200802).the Visiting Scholar Project of Shandong Province of China (No. 20081001)The authors acknowledge financial support from the National Natural Science Foundation of China (No. 20134020)

Novel Y-shaped block copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide), PEG-b-(PNIPAM) ₂, were successfully synthesized through atom transfer radical polymerization (ATRP). A difunctional macroinitiator was prepared by esterification of 2,2-dichloroacetyl chloride with poly(ethylene glycol) monomethyl ether (PEG). The copolymers were obtained via the ATRP of N-isopropylacrylamide (NIPAM) at 30 ℃with CuCl/Me₆TREN as a catalyst system and DMF/H ₂ O (v/v=3:1)n mixture as solvent. The resulting copolymers were characterized by gel permeation chromatography (GPC) and ¹H NMR. These block copolymers show controllable molecular weights and narrow molecular weight distributions (PDI < 1.15). Their phase transition temperatures and the corresponding enthalpy changes in aqueous solution were measured by differential scanning calorimetry (DSC). As a result, the phase transition temperature of PEG ₄₅-b-(PNIPAM ₅₅) ₂ is higher than that of PNIPAM, however,the corresponding enthalpy change is much lower, indicating the significant influence of the macromolecular composition and architecture on the phase transition.
- Y-shaped,
- Block copolymer,
- Poly(ethylene glycol),
- Poly(N-isopropylacrylamide),
- Atom transfer radical polymerization (ATRP)
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