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Citation:
Chu Hang Zhang, Zheng Tao Wang, Yi Ping Yang, Qi Shi Sun. A novel cytotoxic neophysalin from Physalis alkekengi var. francheti[J]. Chinese Chemical Letters,
;2009, 20(11): 1327-1330.
doi:
10.1016/j.cclet.2009.06.005
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A new neophysalin, named 5α-hydroxy-25,27-dihydro-4,7-didehydro-7-deoxyneophysalin A(1), along with three other known neophysalins (2-4) were isolated from the calyxes of Physalis alkekengi L. var. francheti (Mast.) Makino. The structure of 1 was determined by means of 1D and 2D NMR, UV, IR and mass spectra. Compound 1 displayed potent cytotoxicities in vitro against PC-3 and LNCaP cell lines.
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Keywords:
- Physalis alkekengi var. francheti,
- Neophysalin,
- Cytotoxicity
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