Citation: Ning Ma, Hai Feng Tang, Feng Qiu, Hou Wen Lin, Xiang Rong Tian, Wei Zhang. A new polyhydroxysteroidal glycoside from the starfish Anthenea chinensis[J]. Chinese Chemical Letters, ;2009, 20(10): 1231-1234. doi: 10.1016/j.cclet.2009.05.012 shu

A new polyhydroxysteroidal glycoside from the starfish Anthenea chinensis

Ning Ma ^a,b, ,
Hai Feng Tang ^a ,
Feng Qiu ^b ,
Hou Wen Lin ^c ,
Xiang Rong Tian ^a,b ,
Wei Zhang ^a

a Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;
b School of Traditional Chinese Medicines, Shenyang Pharmaceutical University, Shenyang 110016, China;
c Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China

Received Date: 10 March 2009

Fund Project: The authors are grateful to the National Natural Science Foundation of China (No.20502035) and the National High-Tech Research and Development Project (No.2006AA09Z423).

A new polyhydroxysteroidal glycoside, (20R,24R)-16-O-(4-O-methyl-2-acetamido-2-deoxy-β-D-galactopyranosyl)-24-ethyl5a-cholest-8(14)-en-3β,6β,7β,16α-tetrol (anthenoside A, 1), was isolated from the starfish Anthenea chinensis.Its structure was elucidated by extensive spectral analysis and chemical evidences.1 exhibited significant cytotoxicity against human tumor K-562,BEL-7402 and U87MG cells.
- Starfish,
- Anthenea chinensis,
- Polyhydroxysteroidal glycoside,
- Anthenoside A

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