Citation: Rong Xu, Jin Chang Ding, Xi An Chen, Miao Chang Liu, Hua Yue Wu. Gallium trichloride-catalyzed conjugate addition of indole and pyrrole to α,β-unsaturated ketones in aqueous media[J]. Chinese Chemical Letters, ;2009, 20(6): 676-679. doi: 10.1016/j.cclet.2009.01.028 shu

Gallium trichloride-catalyzed conjugate addition of indole and pyrrole to α,β-unsaturated ketones in aqueous media

a Wenzhou Vocational and Technical College, Wenzhou 325035, PR China;
b College of Chemistry and Materials Science, Wenzhou University, Wenzhou 325027, PR China

Received Date: 11 November 2008

Fund Project: We gratefully acknowledge financial support by the Natural Science Foundation of Zhejiang Province (No.Y4051137, Y405015 and Y4080177).

Michael addition of indole and pyrrole to a variety of α, β-unsaturated ketones was efficiently promoted by a catalytic amount of GaCl₃ in aqueous media to afford the corresponding products in good to excellent yields.
- Gallium trichloride,
- Michael addition,
- Indole,
- Pyrrole,
- α,β-Unsaturated ketones
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