Citation: Hui Xu, Xiang Min Wang, Xing Wei, Jing Yuan Li, Ke Liu. A new chalcone from the aerial roots of Ficus microcarpa[J]. Chinese Chemical Letters, ;2009, 20(5): 576-578. doi: 10.1016/j.cclet.2009.01.013 shu

A new chalcone from the aerial roots of Ficus microcarpa

Hui Xu ^a, ,
Xiang Min Wang ^a ,
Xing Wei ^a ,
Jing Yuan Li ^b ,
Ke Liu ^a,b

a School of Pharmacy, Yantai University, Yantai 264005, China;
b Shandong Target Drug Research Co. Ltd, Yantai 264006, China

Received Date: 1 September 2008

Fund Project: We are grateful to the Department of Science & Technology of Shandong Province (No.2007BS02005) and the Visiting Project of the Department of Education of Shandong Province, China (2008) for financial support.

A new flavonoid with chalcone skeleton was isolated from the dried aerial roots of Ficus microcarpa. The structure of the compound was elucidated on the basis of spectral methods including 1D and 2D NMR. The new compound showed weak inhibitory effect on nitric oxide production and cytotoxicity against K562 and PC3 cells.
- Ficus microcarpa,
- Aerial roots,
- Chalcone,
- Nitric oxide(NO)release,
- Cytotoxicity
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