Citation: Nian Jun Xu, Xue Sun, Xiao Jun Yan. A new cyclostellettamine from sponge Amphimedon compressa[J]. Chinese Chemical Letters, ;2007, 18(8): 947-950. doi: 10.1016/j.cclet.2007.06.006 shu

A new cyclostellettamine from sponge Amphimedon compressa

Key Laboratory of Marine Biotechnology, Faculty of Life Science and Biotechnology, Ningbo University, Ningbo 315211, China

Received Date: 1 March 2007

Fund Project: The work was supported by the National Natural Sciences Foundation of China (No. 20472040) and the Natural Science Foundation of Zhejiang Province (No. M40703) and the Pao Yu-kong and Pao Zhao-Long Scholarship.

A new compound, 8, 8'-dienecyclostellettamine, was isolated from the marine sponge Amphimedon compressa. Its structure was elucidated by spectroscopic methods including 1D and 2D NMR, UV, IR, ESI-MS, MALDI-MS techniques. It is probably an important precursor of the manzamine alkoids, and also showed vigorous antibacterial activities.
- Amphimedon compressa,
- Antibacterial,
- 8, 8'-Dienecyclostellettamine
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