Citation: Xin Jian Fu, Shu Qin Cao, Ning Xia Wang, Sheng Zu Zhang, Hong Wang, Ya Jiang Yang. Effect of hydrogen bonding and hydrophobic interaction on the formation of supramolecular hydrogels formed by L-phenylalanine derivative hydrogelator[J]. Chinese Chemical Letters, ;2007, 18(8): 1001-1004. doi: 10.1016/j.cclet.2007.05.015 shu

Effect of hydrogen bonding and hydrophobic interaction on the formation of supramolecular hydrogels formed by L-phenylalanine derivative hydrogelator

Department of Chemistry, Huazhong University of Science and Technology, Wuhan 430074, China

Fund Project: The research work is financially supported by the National Natural Science Foundation of China (No. 20474022).

A new hydrogelator, pyridinium bromide salt of N-6-bromohexanoyl-L-phenylamino octadecane, was synthesized. Supramolecular hydrogels can be formed through the self-assembly of this hydrogelator in water. In this work, D₂O was used instead of H₂O as solvent for FT-IR measurement due to the fact that it is impossible to obtain useful FT-IR information on the hydrogen bonding in water. The investigation of FT-IR and steady-state fluorescence indicated that the driving forces for the self-assembly were mainly hydrogen bonding and hydrophobic interaction. Based on the data of XRD and molecular modeling, the possible mechanism of the formation of hydrogelator aggregates was proposed.
- L-Phenylalanine derivatives,
- Hydrogelator,
- Supramolecular hydrogels
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