Citation: Jiu Xi Chen, Hua Yue Wu, Wei Ke Su. A facile synthesis of 2, 3-dihydro-2-aryl-4(1H)-quinazolinones catalyzed by scandium(Ⅲ) triflate[J]. Chinese Chemical Letters, ;2007, 18(5): 536-538. doi: 10.1016/j.cclet.2007.03.037 shu

A facile synthesis of 2, 3-dihydro-2-aryl-4(1H)-quinazolinones catalyzed by scandium(Ⅲ) triflate

Jiu Xi Chen ^a, ,
Hua Yue Wu ^a ,
Wei Ke Su ^a,b

a College of Chemistry and Materials Science, Wenzhou University, Wenzhou 325027, China;
b College of Pharmaceutical Sciences, Zhejiang University of Technology, Zhejiang Key Laboratory of Pharmaceutical Engineering, Hangzhou 310014, China

Received Date: 27 December 2006

Fund Project: We are grateful to the National Basic Research Program (No. 2003CB114402), the National Natural Science Foundation of China (Nos. 20476098 and 20676123) and Wenzhou University Post-graduate Innovation Foundation (No. YCX0515) for financial support.

2, 3-Dihydro-2-aryl-4(1H)-quinazolinones were prepared in good yields via condensation of o-aminobenzamide with aldehydes promoted by a catalytic amount of Sc (Otf)₃ under mild conditions.
- Scandium(Ⅲ) triflate,
- 2, 3-Dihydro-2-aryl-4(1H)-quinazolinones,
- o-Aminobenzamide
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