Citation: Shan Qian, Li Hai, Lei Tang, Jin Cheng Yang, Yong Wu. Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D₃[J]. Chinese Chemical Letters, ;2007, 18(3): 261-262. doi: 10.1016/j.cclet.2007.01.025 shu

Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D₃

Key Laboratory of Drug Targeting and Novel Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu 610041, China

Received Date: 10 October 2006

Fund Project: Financial support from the National Natural Science Foundation of China (No. 29972013) is gratefully acknowledged.

An optically active intermediate 5 for A-ring of 19-nor-1α,25-dihydroxyvitamin D₃ 2 has been synthesized in five steps, starting from readily available, inexpensive D(+)-xylose 6 with good yield.
- A-ring of 19-nor-1α,25-dihydroxyvitamin D₃,
- Intermediate,
- Synthesis
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