Citation: Ting-jie Song, Hao-jun Liang. CAPABILITY OF DNA-FUELED MOLECULAR MACHINE IN TUNING ASSOCIATION RATE OF DNA-FUNCTIONALIZED GOLD NANOPARTICLES[J]. Chinese Journal of Polymer Science, ;2013, 31(9): 1183-1189. doi: 10.1007/s10118-013-1319-3 shu

CAPABILITY OF DNA-FUELED MOLECULAR MACHINE IN TUNING ASSOCIATION RATE OF DNA-FUNCTIONALIZED GOLD NANOPARTICLES

Ting-jie Song ,
Hao-jun Liang ^,

Corresponding author: Hao-jun Liang,
Received Date: 25 March 2013
Revised Date: 15 May 2013

Fund Project: This work was financially supported by the National Natural Science Foundation of China (Nos. 20934004 and 91127046) and the National Basic Research Program of China (NBRPC) (Nos. 2012CB821500 and 2010CB934500).

The capability of our newly developed DNA-machine-driven strategy in tuning the association rate of DNA-AuNPs was compared with that of linker-addition strategy which has potential practical applications in different fields. The new established strategy shows its superiority to the linker-addition strategy in tuning the association rate of DNA-AuNPs in both pre-incubation treatment and non-incubation treatment conditions since its two components (a complex and a catalyst-oligonucleotide) can be individually optimized to make the machine run at an optimal rate. This strategy will provide a more convenient and flexible option in designing an oligonucleotide detection system and building a complex and versatile device.
- Assembly,
- DNA,
- Enhancing,
- Kinetics,
- Nanoparticle
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