本实验设计合成了铜-焦脱镁叶绿酸a甲酯(Cu-MPPa)，用于活性氧(ROS)介导的癌症治疗和消耗谷胱甘肽，并通过类Fenton反应循环产氧维持细胞内高浓度氧。实验过程中考察了Cu-MPPa的活性氧产生能力、氧气产生能力和谷胱甘肽消耗能力等性能。所合成中间体的结构用质谱进行了表征。这个实验综合了有机化学合成、仪器分析化学和生物化学实验，要求由三名学生组成实验小组，大约需要24学时，旨在培养学生综合创新能力、解决复杂问题能力和培养团队合作精神。

Two new dinuclear lanthanide(Ⅲ) complexes, namely [Ln₂(dbm)₂(HL)₂(CH₃OH)₂]·4CH₃OH [Ln=Tb (1) and Dy (2), Hdbm=dibenzoylmethane] have been synthesized using prepared multidentate Schiff base ligand H₃L (hydroxy-acetic acid(4-diethylamino-2-hydroxy-benzylidene)-hydrazide) with good biological activity. Structure characterizations show that the complex comprises two Ln³⁺ ions, two dbm^- ions, two HL^2- ligands, two CH₃OH molecules, and four free methanol molecules. Each Ln³⁺ ion is eight-coordinated. The two central Ln(Ⅲ) ions are bridged by two μ₂-O atoms leading to a parallelogram [Ln₂O₂] core. The interaction between the compounds (H₃L, 1, and 2) and the calf thymus DNA (CT-DNA) has been further confirmed by UV-Vis spectrometry, fluorescence titration, and cyclic voltammetry. The results showed that both 1 and 2 could undergo insertion with CT-DNA.