Poly(GMA/MA/MBAA) Copolymer Beads: a Highly Efficient Support Immobilizing Penicillin G Acylase

Ping XUE Guan Zhong LU Wan Yi LIU

引用本文: Ping XUE,  Guan Zhong LU,  Wan Yi LIU. Poly(GMA/MA/MBAA) Copolymer Beads: a Highly Efficient Support Immobilizing Penicillin G Acylase[J]. Chinese Chemical Letters, 2006, 17(1): 129-132. shu
Citation:  Ping XUE,  Guan Zhong LU,  Wan Yi LIU. Poly(GMA/MA/MBAA) Copolymer Beads: a Highly Efficient Support Immobilizing Penicillin G Acylase[J]. Chinese Chemical Letters, 2006, 17(1): 129-132. shu

Poly(GMA/MA/MBAA) Copolymer Beads: a Highly Efficient Support Immobilizing Penicillin G Acylase

  • 基金项目:

    This work was supported by the National Natural Science Foundation of China (No. 20564002) and the State Key Program of Fundamental Research (No. 2004CCA05900).

摘要: The hydrophilic, macroporous and beaded ternary copolymer of glycidyl methacrylate (GMA)/methacrylamide(MA)/N, N'-methylene-bis(acrylamide)(MBAA)was synthesized using the industrial agents by inverse suspension polymerization. The apparent activity of the immobilized penicillin G acylase reached 1096 IU/g for hydrolysis penicillin G on the beads with diameter of 0.11-0.13 mm, and it changed hardly after 50 cycles. It can be expected to be a good potential in industrial application.

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  • 收稿日期:  2005-04-28
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