引用本文:
Ling Ling Zhao, Yue Gai, Hisayoshi Kobayashi, Chang Qi Hu, Hui Ping Zhang. 5'-Hydroxyzearalenol, a new β-resorcylic macrolide from Fusarium sp. 05ABR26[J]. Chinese Chemical Letters,
2008, 19(9): 1089-1092.
doi:
10.1016/j.cclet.2008.06.025
Citation: Ling Ling Zhao, Yue Gai, Hisayoshi Kobayashi, Chang Qi Hu, Hui Ping Zhang. 5'-Hydroxyzearalenol, a new β-resorcylic macrolide from Fusarium sp. 05ABR26[J]. Chinese Chemical Letters, 2008, 19(9): 1089-1092. doi: 10.1016/j.cclet.2008.06.025
Citation: Ling Ling Zhao, Yue Gai, Hisayoshi Kobayashi, Chang Qi Hu, Hui Ping Zhang. 5'-Hydroxyzearalenol, a new β-resorcylic macrolide from Fusarium sp. 05ABR26[J]. Chinese Chemical Letters, 2008, 19(9): 1089-1092. doi: 10.1016/j.cclet.2008.06.025
5'-Hydroxyzearalenol, a new β-resorcylic macrolide from Fusarium sp. 05ABR26
摘要:
A new β-resorcylic maerolide, 5'-hydroxyzearalenol (1), was isolated from the culture broth of a marine-derived fungus Fusarium sp. 05ABR26. Three known compounds, zearalenone (2), 8'-hydroxyzearalenone (3) and zearalenol (4) were also isolated. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data and single-crystal X-ray diffraction data. Compound 2 displayed potent inhibitory activity against Pyricularia oryzae with a MIC value of 6.25 μg/mL, while compound 3 was much less active; however, 1 and 4 showed no obvious activity.
English
5'-Hydroxyzearalenol, a new β-resorcylic macrolide from Fusarium sp. 05ABR26
Abstract:
A new β-resorcylic maerolide, 5'-hydroxyzearalenol (1), was isolated from the culture broth of a marine-derived fungus Fusarium sp. 05ABR26. Three known compounds, zearalenone (2), 8'-hydroxyzearalenone (3) and zearalenol (4) were also isolated. The structure and relative stereochemistry of 1 were elucidated on the basis of spectroscopic data and single-crystal X-ray diffraction data. Compound 2 displayed potent inhibitory activity against Pyricularia oryzae with a MIC value of 6.25 μg/mL, while compound 3 was much less active; however, 1 and 4 showed no obvious activity.
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Key words:
- 5'-Hydroxyzearalenol
- / Fusarium sp.
- / X-ray diffraction data
- / Pyricularia oryzae
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