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• Selenium (Se) is a unique chalcogen element with broad application scopes [1-7]. The atomic radius of Se is larger than sulphur (S), resulting in the weaker binding force to its outer electrons. Thus, Se is more easily oxidized than S. Comparatively, the hybrid orbital and bond length of Se═O are longer than that of S═O, resulting in the weaker π bonds that can be easily reduced [8]. The above features make Se to be a good oxygen carrier that can be employed as the catalyst for oxidation reactions [9]. In 2019, we found that, introducing iron salts into the organoselenium catalyst system could significantly enhance its activity for oxidative deoximation reactions, as being reflected by the fact that molecular oxygen could be employed as the oxidant in the presence of the PhCH₂Se(O)OH/FeSO₄ bi-component catalytic system [10]. In the reaction, Se catalysed the oxidative deoximation reaction, while Fe facilitates the activation of molecular oxygen, i.e., catalysed by Fe, the aerobic oxidation of low valent Se to the active Se═O could be achieved, resulting in the less consumption of chemical oxidants such as H₂O₂. Later, a series of bi-component Se/metal catalysts have been developed such as the Se/Cu [11], Se/Ag [12], Se/Mn [13], and Se/Al [14].

  On the other hand, heterogeneous catalysts are practical for large-scale applications [15-19], while using iron as catalyst component is also preferable for the low cost of the metal [20-25]. Thus, developing heterogeneous Se/Fe catalysts may be a good research topic with industrial application potential. However, the present technologies for preparing Se/Fe materials are not practical. For example, Se/Fe materials could be fabricated via the nucleophilic addition at Fe₂O₃ with NaHSe, which was generated in situ by the reduction of Se powder with NaBH₄ (Scheme 1, Method 1) [26]. The process may release H₂Se, which is a toxic gas hazardous to the environments. Moreover, H₂ gas is also generated during the reaction, and it must be carefully treated to avoid explosion accident in large-scale production [27]. Another method for preparing Se/Fe catalyst is by calcining the Se and Fe powders with melamine, but it requires high calcination temperature at 500 ℃ and most of the weight of melamine lost during the process (Scheme 1, Method 2) [28]. Se/Fe material can be prepared by calcining methylselenized glucose [29] with FeCl₃ [30]. However, despite the high calcining temperature (500 ℃), the expensive price of methylselenized glucose may bottleneck the application of the method in industry (Scheme 1, Method 3). Recently, we developed a new concise method to fabricate Se/Fe materials more efficiently (Scheme 1, Method 4). Herein, we wish to report our findings.

  Scheme 1

  

  Scheme 1.  Comparison of the methods.

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  The material was fabricated via the co-precipitation of iron salt with selenium species under alkaline conditions. Heating selenium powder with aqueous NaOH initially led to the mixture of Na₂Se and Na₂SeO₃ via the disproportionated reaction of Se⁰ to Se²⁻ and Se⁴⁺ (Scheme 1, Method 4). After cooling to room temperature, aqueous Fe(NO₃)₃ was added to precipitate selenium. The precipitations were dried at 100 ℃ in a simple bake out furnace just in open air to afford the iron oxide-supported selenium marked as Se/FeO_x·yH₂O.

  Transmission electron microscopy (TEM) image shows that selenium dispersed uniformly on the surface of the material, and it may be in amorphous state (Fig. 1a). Energy dispersive X-ray spectroscopy (EDX) confirmed the successful loading of selenium onto the iron oxide support (Fig. 1b). High angle annular dark field scanning electron microscopy (HAADF-STEM) and element mapping images can effectively reflect the composition and dispersion of the elements in the material. HAADF-STEM images are highly sensitive to changes in atomic number of atoms in the sample (Z-contrast images). Specifically, the contrast intensity of Z is directly proportional to the square of the atomic number [31]. Therefore, the bright area may be attributed to the Se element in the HAADF-STEM image of Se/FeO_x·yH₂O (Figs. 1c and d). The element mapping images in Figs. 1e–h reflect the uniform dispersion of Se, Fe, O, and Na elements. Dispersive distribution of Se indicates that the element may also be involved by physical adsorption (Fig. 1e).

  Figure 1

  

  Figure 1.  Composition analysis of Se/FeO_x·yH₂O.

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  Fourier-transform infrared (FT-IR) and ultraviolet-visible (UV–vis) analyses of the materials were then conducted to get the information of the functional groups in the materials. Unselenized Fe₂O₃·xH₂O was prepared in similar method and analysed for comparison. The IR spectra of Se/FeO_x·yH₂O and Fe₂O₃·xH₂O were generally the same, and no additional peak emerged. This indicates that the selenium content in the material was particularly low, and the formed selenium-containing bonds were difficult to be observed in its IR spectrum (Fig. 2a). This conclusion was then verified by the inductively coupled plasma mass spectroscopy (ICP-MS) analysis of the material, which verified that selenium content in Se/FeO_x·yH₂O was only 3.5%. IR spectra indicated that the water-content of Fe₂O₃·xH₂O was higher than that of Se/FeO_x·yH₂O, as being reflected by the even stronger signals at ca. 3500 cm⁻¹. The influence of water content was more significant in UV–vis spectra, and it caused the red-shift in the spectrum and led to the peaks at 250–350 nm (Fig. 2b).

  Figure 2

  

  Figure 2.  IR (a) and UV–vis (b) spectra of Fe₂O₃·xH₂O and Se/FeO_x·yH₂O.

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  As a material containing both selenium and iron, Se/FeO_x·yH₂O was supposed to be a nice catalyst for oxidation reactions. Its catalytic activity was initially evaluated via the oxidation reaction of anthracene to anthraquinone (Eq. 1). Anthracene is a pollutant that was abundantly produced from coal chemical industry, while anthraquinone is now a basic raw material for the synthesis of organic light-emitting materials (OLEMs), which are electronic chemicals of profound market prospect [32-34]. Thus, the reaction is a significant industrial process and deserves investigations.

  (1)

  As shown in Fig. 3a, catalysed by Se/FeO_x·yH₂O, the oxidation of anthracene occurred smoothly and produced the desired anthraquinone in good yields. As a heterogeneous catalyst with magnetic features, Se/FeO_x·yH₂O could be removed from the mixture by magnetic separation after reaction. It is reusable, and the recycled catalyst could be directly reused without deactivation. In the reactions, both the conversion ratio of anthracene and the selectivity of anthraquinone were over 90%, showing sufficient utilization of the atoms in starting materials from the industrial viewpoint (Fig. 3a). The catalytic activity of unselenized Fe₂O₃·xH₂O was also tested for comparison, but led to poor anthracene conversion, and the selectivity of anthraquinone also decreased (Fig. 3b). Thus, it may be concluded that the oxygen-carrier properties of selenium endow the material good catalytic activity for oxidation reactions, which has been well summarized by literatures [35-40].

  Figure 3

  

  Figure 3.  Studies on the materials: (a) Recycling and reusing of Se/FeO_x^.yH₂O. (b) Recycling and reusing of Fe₂O₃·xH₂O. Adsorption of anthracene on Se/FeO_x·yH₂O (c) and Fe₂O₃·xH₂O (d).

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  It has been reported that selenization may change the surface properties of the materials and affect the mass-transfer processes during the catalytic reactions [41,42]. Thus, the elevated catalytic activity of Se/FeO_x·yH₂O versus unselenized Fe₂O₃·xH₂O may also attribute to the improved mass-transfer properties of the materials. To verify or exclude this possibility, anthracene adsorption experiments were performed with Se/FeO_x·yH₂O and Fe₂O₃·xH₂O. As shown in Fig. 3c, ca. 31% of anthracene was adsorbed on Se/FeO_x·yH₂O after 24 h immersing, but for Fe₂O₃·xH₂O, this value was only 22% after the same time immersing (Fig. 3d). The result clearly demonstrated that the mass-transfer process on Se/FeO_x·yH₂O was better than the unselenized Fe₂O₃·xH₂O.

  On the other hand, polyenes are common pollutants in pharmaceutical industry [43,44], and they may be treated by the oxidative degradation splitting the C═C bond. Our recent investigations have demonstrated that the oxidative C═C cleavage reaction could be catalysed by selenium, while iron significantly promoted the catalytic activity [45,46]. Thus, as a heterogeneous catalyst containing both selenium and iron, Se/FeO_x·yH₂O may be applied in polyene degradation reaction. In this work, we chose the degradation of β-carotene as the model reaction to evaluate the catalytic activity of Se/FeO_x·yH₂O. As shown in Fig. 4a, the colour of β-carotene faded smoothly during the process. Moreover, UV–vis spectra in Fig. 4b clearly indicated the blue shift of the samples along with the reaction time, reflecting the C═C bond cleavage leading to the colourless small molecules. Mass-spectra of the reaction mixtures (Figs. S2–S5 in Supporting information) could verify that the Se/FeO_x·yH₂O-catalyzed oxidation reaction of β-carotene could result in the C═C bond splitting leading to produce a variety of fragments such as the β-ionone.

  Figure 4

  

  Figure 4.  (a) Photographs and (b) UV–vis spectra of the samples of β-carotene degradation reactions with Se/FeO_x·yH₂O.

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  X-ray photoelectron spectroscopy (XPS) analysis was then conducted to evaluate the stability of the catalysts during the reaction processes. In the XPS spectra, the signals of Se 3d_5/2 and Se 3d_3/2 of fresh Se/FeO_x·yH₂O emerged at 55.8 and 56.8 eV respectively. They did not change much after the five times reaction (Fig. 3a), showing that the valence of selenium was stable during the catalytic oxidation reaction process (Fig. 5a). In the Fe 2p spectra, signals at 711.5 and 725.1 eV reflected Fe 2p_3/2 and Fe 2p_1/2 respectively, and their compositions were generally stable during the reaction process (Fig. 5b). There were only Se⁴⁺ and Se²⁺ species in the material, while the Se²⁻ species disappeared. For iron, both Fe²⁺ and Fe³⁺ species were observed in XPS spectra. This phenomenon demonstrated that the redox reaction occurred between the disproportionated reaction-generated reductive Se²⁻ and the oxidative Fe³⁺. The O 1s spectra of the materials (Fig. S1 in Supporting information) indicated there were three kinds of oxygen, such as O_L, O_V and the hydroxyl oxygen, and the strength of the signals were determined by the concentration of the oxygen vacancy. The content of hydroxyl oxygen decreased obviously after reaction, reflecting the aging process releasing water from the material.

  Figure 5

  

  Figure 5.  XPS analysis of Se/FeOx.

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  In conclusion, we have reported a new method for preparing Se/Fe materials concisely. It was found that, just by heating Se with NaOH could lead to the water soluble selenium salts such as Na₂Se and Na₂SeO₃, which were precipitated by Fe(NO₃)₃ and led to Se/FeO_x·yH₂O after simple drying at 100 ℃. The material could catalyse the selective oxidation of anthracene to produce anthraquinone, a basic material of OLEM industry. It is also applicable for polyene degradation. Indeed, the purpose of this work is not only limited on the synthesis of anthraquinone or the degradation of polyene. It proposes a new approach for the rapid synthesis of selenium containing materials, which will have a profound impact in the field of selenium science and materials and industry.

  Declaration of competing interest

  The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

  CRediT authorship contribution statement

  Xiaoxue Li: Writing – original draft, Investigation. Hongwei Zhou: Writing – review & editing, Supervision. Rongrong Qian: Writing – original draft. Xu Zhang: Supervision, Investigation. Lei Yu: Writing – review & editing, Supervision, Project administration, Conceptualization.

  Acknowledgments

  We thank the Jiangsu Provincial Six Talent Peaks Project (No. XCL-090), the Cooperation Project of Yangzhou City with Yangzhou University (No. YZ2023209), Jiaxing Key Laboratory for Creation of Animal Models & Synthesis of Lead Compounds of New Drug (No. jxsz21006), and the Priority Academic Program Development of Jiangsu Higher Education Institutions for support.

  Supplementary materials

  Supplementary material associated with this article can be found, in the online version, at doi:10.1016/j.cclet.2024.110036.

  
  
• 1. [1]

     D. Yong, J. Tian, R. Yang, Q. Wu, X. Zhang, Chin. J. Org. Chem. 44 (2024) 1343–1347. doi: 10.6023/cjoc202310020

  2. [2]

     J. Li, Q. Shi, Y. Xue, et al., Chin. Chem. Lett. 35 (2024) 109239. doi: 10.1016/j.cclet.2023.109239

  3. [3]

     L. Xian, Q. Li, T. Li, L. Yu, Chin. Chem. Lett. 34 (2023) 107878. doi: 10.1016/j.cclet.2022.107878

  4. [4]

     W. Ding, S. Wang, J. Gu, L. Yu, Chin. Chem. Lett. 34 (2023) 108043. doi: 10.1016/j.cclet.2022.108043

  5. [5]

     J. Zhou, X. Xu, H. Wu, et al., Nat. Energy 8 (2023) 526–535. doi: 10.1038/s41560-023-01251-6

  6. [6]

     Z. Zhao, S. Laps, J.S. Gichtin, N. Metanis, Nat. Rev. Chem. 8 (2024) 211–229. doi: 10.1038/s41570-024-00579-1

  7. [7]

     Z. Wang, X. Wang, Q. Li, et al., Chin. Chem. Lett. 35 (2024) 109058. doi: 10.1016/j.cclet.2023.109058

  8. [8]

     W. Hou, H. Xu, J. Med. Chem. 65 (2022) 4436–4456. doi: 10.1021/acs.jmedchem.1c01859

  9. [9]

     A.J. Pacuła-Miszewska, L. Sancineto, Oxygen-transfer reactions catalyzed by organoselenium compounds, in: E.J. Lenardão, C. Santi, G. Perin, D. Alves (Eds.), Organochalcogen Compounds, Elsevier, 2022, pp. 219–249.

  10. [10]

      C. Chen, X. Zhang, H. Cao, et al., Adv. Synth. Catal. 361 (2019) 603–610. doi: 10.1002/adsc.201801163

  11. [11]

      C. Chen, Z. Cao, X. Zhang, et al., Chin. J. Chem. 38 (2020) 1045–1051. doi: 10.1002/cjoc.202000089

  12. [12]

      F. Liu, J. Zhan, Y. Sun, X. Jing, Chin. J. Org. Chem. 41 (2021) 2099–2104. doi: 10.6023/cjoc202011012

  13. [13]

      Y. Zeng, T. Chen, X. Zhang, et al., Appl. Organomet. Chem. 36 (2022) e6658. doi: 10.1002/aoc.6658

  14. [14]

      X. Zhang, R. Zhou, Z. Qi, et al., Reat. Chem. Eng. 7 (2022) 1990–1996. doi: 10.1039/d2re00190j

  15. [15]

      R.N. Yi, W.M. He, Chin. Chem. Lett. 35 (2024) 109253. doi: 10.1016/j.cclet.2023.109253

  16. [16]

      F.L. Zeng, H.L. Zhu, R.N. Wang, et al., Chin. J. Catal. 46 (2023) 157–166. doi: 10.1016/S1872-2067(23)64391-8

  17. [17]

      Y.H. Lu, C. Wu, J.C. Hou, et al., ACS Catal. 13 (2023) 13071–13076. doi: 10.1021/acscatal.3c02268

  18. [18]

      H.Y. Song, J. Jiang, C. Wu, et al., Green Chem. 25 (2023) 3292–3296. doi: 10.1039/d2gc04843d

  19. [19]

      W.T. Ouyang, H.T. Ji, J. Jiang, et al., Chem. Commun. 59 (2023) 14029–14032. doi: 10.1039/d3cc04020h

  20. [20]

      G. Zhang, C. Zhang, Y. Tian, F. Chen, Org. Lett. 25 (2023) 917–922. doi: 10.1021/acs.orglett.2c04185

  21. [21]

      H. Zhang, T. Yang, H. Zhou, et al., Appl Catal. B 342 (2024) 123391. doi: 10.1016/j.apcatb.2023.123391

  22. [22]

      H. Sun, J. Wu, F. Tian, et al., Catal. Sci. Technol. 14 (2024) 660–666. doi: 10.1039/D3CY01618H

  23. [23]

      Z. Han, Y. Zhu, X. Yao, et al., Appl. Catal. B 337 (2023) 122961. doi: 10.1016/j.apcatb.2023.122961

  24. [24]

      C. Pei, Y. Gu, Z. Liu, X. Yu, L. Feng, ChemSusChem 12 (2019) 3849–3855. doi: 10.1002/cssc.201901153

  25. [25]

      Y. Li, L. Zhang, Z. Zhang, et al., Adv. Synth. Catal. 358 (2016) 2148–2155. doi: 10.1002/adsc.201600165

  26. [26]

      X. Chen, J. Mao, C. Liu, et al., Chin. Chem. Lett. 31 (2020) 3205–3208. doi: 10.1016/j.cclet.2020.07.031

  27. [27]

      W. Zhou, P. Li, J. Liu, L. Yu, Ind. Eng. Chem. Res. 59 (2020) 10763–10767. doi: 10.1021/acs.iecr.0c01147

  28. [28]

      W. Zhou, X. Xiao, Y. Liu, X. Zhang, Chin. J. Org. Chem. 42 (2022) 1849–1855. doi: 10.6023/cjoc202201023

  29. [29]

      Q. Wang, P. Li, T. Li, et al., Ind. Eng. Chem. Res. 60 (2021) 8659–8663. doi: 10.1021/acs.iecr.1c01437

  30. [30]

      H. Cao, P. Li, X. Jing, H. Zhou, Chin. J. Org. Chem. 42 (2022) 3890–3895. doi: 10.6023/cjoc202205005

  31. [31]

      K. Sohlberg, T.J. Pennycook, W. Zhou, S.J. Pennycook, Phys. Chem. Chem. Phys. 17 (2015) 398–406. doi: 10.1039/C4CP04289A

  32. [32]

      Y. Liu, Z. Li, Y. Xu, et al., ACS. Appl. Mater. Interfaces 16 (2024) 9436–9442. doi: 10.1021/acsami.3c16293

  33. [33]

      N.N. Ayare, P.O. Gupta, M.C. Sreenath, et al., Spectrochim. Acta A 246 (2021) 119017. doi: 10.1016/j.saa.2020.119017

  34. [34]

      L. Chen, Y. Chen, H. Fu, et al., Adv. Sci. 7 (2020) 2000803. doi: 10.1002/advs.202000803

  35. [35]

      J.T. Stadel, T.G. Back, Chem. Eur. J. 30 (2024) e202304074. doi: 10.1002/chem.202304074

  36. [36]

      S. Dyjak, B.J. Jankiewicz, S. Kaniecki, W. Kiciński, Green Chem. 26 (2024) 2985–3020. doi: 10.1039/d3gc04804g

  37. [37]

      X. Xiao, C. Guan, J. Xu, W. Fu, L. Yu, Green Chem. 23 (2021) 4647–4655. doi: 10.1039/d1gc00961c

  38. [38]

      H. Cao, R. Qian, L. Yu, Catal. Sci. Technol. 10 (2020) 3113–3121. doi: 10.1039/d0cy00400f

  39. [39]

      F.V. Singh, T. Wirth, Catal. Sci. Technol. 9 (2019) 1073–1091. doi: 10.1039/c8cy02274g

  40. [40]

      L. Shao, Y. Li, J. Lu, X. Jiang, Org. Chem. Front. 6 (2019) 2999–3041. doi: 10.1039/c9qo00620f

  41. [41]

      K. Cao, X. Deng, T. Chen, Q. Zhang, L. Yu, J. Mater. Chem. A 7 (2019) 10918–10923. doi: 10.1039/c9ta00846b

  42. [42]

      P. Li, Z. Qi, L. Yu, H. Zhou, Catal. Sci. Technol. 12 (2022) 2241–2247. doi: 10.1039/d1cy02274a

  43. [43]

      S.K. Alharbi, W.E. Price, Curr. Pollut. Rep. 3 (2017) 268–280. doi: 10.1007/s40726-017-0072-6

  44. [44]

      Y. Miao, Y. Zhao, G. Waterhouse, et al., Nat. Commun. 14 (2023) 4242. doi: 10.1038/s41467-023-40005-6

  45. [45]

      X. Li, H. Hua, Y. Liu, L. Yu, Org. Lett. 25 (2023) 6720–6724. doi: 10.1021/acs.orglett.3c02569

  46. [46]

      T. Wang, X. Jing, C. Chen, L. Yu, J. Org. Chem. 82 (2017) 9342–9349. doi: 10.1021/acs.joc.7b01245

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  Scheme 1  Comparison of the methods.

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  Figure 1  Composition analysis of Se/FeO_x·yH₂O.

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  Figure 2  IR (a) and UV–vis (b) spectra of Fe₂O₃·xH₂O and Se/FeO_x·yH₂O.

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  Figure 3  Studies on the materials: (a) Recycling and reusing of Se/FeO_x^.yH₂O. (b) Recycling and reusing of Fe₂O₃·xH₂O. Adsorption of anthracene on Se/FeO_x·yH₂O (c) and Fe₂O₃·xH₂O (d).

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  Figure 4  (a) Photographs and (b) UV–vis spectra of the samples of β-carotene degradation reactions with Se/FeO_x·yH₂O.

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  Figure 5  XPS analysis of Se/FeOx.

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