引用本文:
Xin Ying Zhang, Ying Ying Qu, Xue Sen Fan. An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions[J]. Chinese Chemical Letters,
2010, 21(10): 1191-1194.
doi:
10.1016/j.cclet.2010.04.037
Citation: Xin Ying Zhang, Ying Ying Qu, Xue Sen Fan. An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions[J]. Chinese Chemical Letters, 2010, 21(10): 1191-1194. doi: 10.1016/j.cclet.2010.04.037
Citation: Xin Ying Zhang, Ying Ying Qu, Xue Sen Fan. An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions[J]. Chinese Chemical Letters, 2010, 21(10): 1191-1194. doi: 10.1016/j.cclet.2010.04.037
An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions
摘要:
An environmentally benign and highly efficient one-pot preparation of α-aminophosphonates under solvent-free conditions was developed. By employing this method, 5-aminophosphonate substituted pyrimidine nucleosides were synthesized in good to excellent yields starting from 5-formyl-2'-deoxyuridine, aniline and dimethylphosphite.
English
An efficient and green preparation of 5-aminophosphonate substituted pyrimidine nucleosides under solvent-free conditions
Abstract:
An environmentally benign and highly efficient one-pot preparation of α-aminophosphonates under solvent-free conditions was developed. By employing this method, 5-aminophosphonate substituted pyrimidine nucleosides were synthesized in good to excellent yields starting from 5-formyl-2'-deoxyuridine, aniline and dimethylphosphite.
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