引用本文:
Ying CHEN, Ruo Yun CHEN, De Quan YU. A New Annonaceous Acetogenin from Goniothalamus Gardneri[J]. Chinese Chemical Letters,
1997, 8(11): 971-974.
Citation: Ying CHEN, Ruo Yun CHEN, De Quan YU. A New Annonaceous Acetogenin from Goniothalamus Gardneri[J]. Chinese Chemical Letters, 1997, 8(11): 971-974.
Citation: Ying CHEN, Ruo Yun CHEN, De Quan YU. A New Annonaceous Acetogenin from Goniothalamus Gardneri[J]. Chinese Chemical Letters, 1997, 8(11): 971-974.
A New Annonaceous Acetogenin from Goniothalamus Gardneri
摘要:
A new monotetrahydrofuran Annonaceous acetogenin,gardnerin (1) was isolated from the roots of Goniothalamus gardneri Hook.f.et.Thoms.This compound possesses five hydroxyl groups,with two hydroxyl groups at C-8 and C-10 positions.The absolute stereochemistry at 8-OH and 10-OH positions was determined by converting 1 to its ketolactone isomer,2,4-cis/trans gardnerin.Bioactivities of this new compound against human tumor cell lines are reported.Five known acetogenin compounds gigantetrocin A and B,annonacin,goniothalamicin,isoannonacin were also found.
English
A New Annonaceous Acetogenin from Goniothalamus Gardneri
Abstract:
A new monotetrahydrofuran Annonaceous acetogenin,gardnerin (1) was isolated from the roots of Goniothalamus gardneri Hook.f.et.Thoms.This compound possesses five hydroxyl groups,with two hydroxyl groups at C-8 and C-10 positions.The absolute stereochemistry at 8-OH and 10-OH positions was determined by converting 1 to its ketolactone isomer,2,4-cis/trans gardnerin.Bioactivities of this new compound against human tumor cell lines are reported.Five known acetogenin compounds gigantetrocin A and B,annonacin,goniothalamicin,isoannonacin were also found.
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