1-Ethyl-2-Fluoro Pyridinium Salt:A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis

Peng LI Jie Cheng XU

引用本文: Peng LI,  Jie Cheng XU. 1-Ethyl-2-Fluoro Pyridinium Salt:A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis[J]. Chinese Chemical Letters, 2000, 11(5): 377-380. shu
Citation:  Peng LI,  Jie Cheng XU. 1-Ethyl-2-Fluoro Pyridinium Salt:A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis[J]. Chinese Chemical Letters, 2000, 11(5): 377-380. shu

1-Ethyl-2-Fluoro Pyridinium Salt:A Highly Efficient Coupling Reagents for Sterically Hindered Peptide Synthesis

  • 基金项目:

    This work was financially supported by the National Natural Science Foundation of China (9772045).

摘要: 1-Ethyl-2-fluoropyridinium tetrafluoroborate(FEP)was shown to be a very efficient coupling reagent for the synthesis of the hindered peptide with fast reaction speed,low racemization and good yields.

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  • 收稿日期:  1999-10-22
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