Synthesis of aromatic-linked polyamine macrocyclic derivatives as HIV-1 entry inhibitors

• Jing Su ^a, ,
• Yao Liu ^b, ,
• Zhi Bing Zheng ^c, ,
• Jun Hai Xiao ^c, ,
• Hong Lu ^b, ,
• Wu Zhong ^c, ,
• Li Li Wang ^c, ,
• Shi Bo Jiang ^b, ,
• Song Li ^c,

• a School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China;

• b School of Pharmacy, Jilin University, Changchun 130021, China;

• c Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;

• d Lindsley F. Kimball Research Institute, the New York Blood Center, New York, NY 10021, USA

• Received Date: 13 June 2007
  
• Fund Project:

  This work was supported by the National Basic Research Program of China (973 project:No.2004CB518908) and the National Natural Science Foundation of China (No.30472093) to SL and the Outstanding Overseas Chinese Scholars Fund of Chinese Academy of Sciences (No.2005-2-6) to S.J.