引用本文:
Yu Li XIE, Qin ZHU, Xing Rong QIN, Yu Yuan XIE. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes[J]. Chinese Chemical Letters,
2003, 14(1): 25-28.
Citation: Yu Li XIE, Qin ZHU, Xing Rong QIN, Yu Yuan XIE. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes[J]. Chinese Chemical Letters, 2003, 14(1): 25-28.

Citation: Yu Li XIE, Qin ZHU, Xing Rong QIN, Yu Yuan XIE. An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes[J]. Chinese Chemical Letters, 2003, 14(1): 25-28.

An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes
摘要:
A simple and efficient procedure for synthesis of 1-hydroxymcthylene-1,1-bisphosphoates from aldehydes is deseribed. This method was applied to the synthesis of nowel catcchol substituted bisphosphonatcs as the anti-ostcoporosis agents.
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关键词:
- Bisphosphonate
- / aldehydes
- / catechol
- / anti-osteoporosis
English
An Efficient Synthesis of Aromatic 1-Hydroxymethylene-1,1-bisphosphonates from Aldehydes
Abstract:
A simple and efficient procedure for synthesis of 1-hydroxymcthylene-1,1-bisphosphoates from aldehydes is deseribed. This method was applied to the synthesis of nowel catcchol substituted bisphosphonatcs as the anti-ostcoporosis agents.
-
Key words:
- Bisphosphonate
- / aldehydes
- / catechol
- / anti-osteoporosis

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