引用本文:
Jin Jiang, Jiu Yu Liu, Hui Yuan Guo. The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones:Analogues of gemifloxacin[J]. Chinese Chemical Letters,
2007, 18(10): 1169-1172.
doi:
10.1016/j.cclet.2007.07.030
Citation: Jin Jiang, Jiu Yu Liu, Hui Yuan Guo. The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones:Analogues of gemifloxacin[J]. Chinese Chemical Letters, 2007, 18(10): 1169-1172. doi: 10.1016/j.cclet.2007.07.030
Citation: Jin Jiang, Jiu Yu Liu, Hui Yuan Guo. The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones:Analogues of gemifloxacin[J]. Chinese Chemical Letters, 2007, 18(10): 1169-1172. doi: 10.1016/j.cclet.2007.07.030
The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones:Analogues of gemifloxacin
摘要:
7-[4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-difluoromethoxy-1, 4-dihydro-4-oxoquino-line-3-carboxylic acid and its analogues have been prepared and evaluated for antibacterial activity in vitro.
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关键词:
- Quinolone
- / Synthesis
- / Antibacterial activity
English
The synthesis and activity in vitro of a series of 8-difluoromethoxy quinolones:Analogues of gemifloxacin
Abstract:
7-[4-(Aminomethyl)-3-(methoxyimino)pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-8-difluoromethoxy-1, 4-dihydro-4-oxoquino-line-3-carboxylic acid and its analogues have been prepared and evaluated for antibacterial activity in vitro.
-
Key words:
- Quinolone
- / Synthesis
- / Antibacterial activity
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