引用本文:
Xian Ping DAI, Xing Zhou LI, Zhi Bing ZHENG, Song LI. Synthesis and Biological Evaluation of Novel 1, 5-Diarylpyrazole-3-carboxamide Compounds as Inhibitors of ALK5[J]. Chinese Chemical Letters,
2006, 17(5): 609-612.
Citation: Xian Ping DAI, Xing Zhou LI, Zhi Bing ZHENG, Song LI. Synthesis and Biological Evaluation of Novel 1, 5-Diarylpyrazole-3-carboxamide Compounds as Inhibitors of ALK5[J]. Chinese Chemical Letters, 2006, 17(5): 609-612.

Citation: Xian Ping DAI, Xing Zhou LI, Zhi Bing ZHENG, Song LI. Synthesis and Biological Evaluation of Novel 1, 5-Diarylpyrazole-3-carboxamide Compounds as Inhibitors of ALK5[J]. Chinese Chemical Letters, 2006, 17(5): 609-612.

Synthesis and Biological Evaluation of Novel 1, 5-Diarylpyrazole-3-carboxamide Compounds as Inhibitors of ALK5
摘要:
Ten new 1, 5-diarylpyrazole-3-carboxamide compounds were synthesized and their structures were identified by 1H-NMR and FAB-MS. The primary biological tests showed that compound 4j exhibited some ALK5 inhibitory activity at concentration of 1μmol/L.
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关键词:
- 1
- / 5-Diarylpyrazole-3-carboxamide
- / synthesis
- / inhibitors
- / ALK5
English
Synthesis and Biological Evaluation of Novel 1, 5-Diarylpyrazole-3-carboxamide Compounds as Inhibitors of ALK5
Abstract:
Ten new 1, 5-diarylpyrazole-3-carboxamide compounds were synthesized and their structures were identified by 1H-NMR and FAB-MS. The primary biological tests showed that compound 4j exhibited some ALK5 inhibitory activity at concentration of 1μmol/L.
-
Key words:
- 1
- / 5-Diarylpyrazole-3-carboxamide
- / synthesis
- / inhibitors
- / ALK5

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