引用本文:
Dan Dan HAN, Chun WANG, Zhi WANG, Qiu Hua WU, Xiao Huan ZANG. On-line Sweeping Sample Concentration in Micellar Electrokinetic Chromatography with Enhanced Sensitivity for the Determination of Carbamazepine in Human Serum[J]. Chinese Chemical Letters,
2006, 17(7): 953-956.
Citation: Dan Dan HAN, Chun WANG, Zhi WANG, Qiu Hua WU, Xiao Huan ZANG. On-line Sweeping Sample Concentration in Micellar Electrokinetic Chromatography with Enhanced Sensitivity for the Determination of Carbamazepine in Human Serum[J]. Chinese Chemical Letters, 2006, 17(7): 953-956.

Citation: Dan Dan HAN, Chun WANG, Zhi WANG, Qiu Hua WU, Xiao Huan ZANG. On-line Sweeping Sample Concentration in Micellar Electrokinetic Chromatography with Enhanced Sensitivity for the Determination of Carbamazepine in Human Serum[J]. Chinese Chemical Letters, 2006, 17(7): 953-956.

On-line Sweeping Sample Concentration in Micellar Electrokinetic Chromatography with Enhanced Sensitivity for the Determination of Carbamazepine in Human Serum
摘要:
A sensitive and simple micellar electrokinetic chromatography (MEKC) method was developed for the determination of antiepileptic drug, carbamazepine (CBZ), using sweeping on-line concentration method with photodiode array detection. Under the optimal conditions, the calbration curve was linear oevr a range of 1.5-40μg·mL-1for CBZ with a correlation clefficient of 0.998.The detection limt(S/N=3:1)of CBZ was 0.10μg·mL-1.The sweeping-MEKC method has been successfully applied to the analysis of CBZ in human serum.
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关键词:
- On-line concentration
- / carbamazepine
- / MEKC
- / sweeping
- / human serum
English
On-line Sweeping Sample Concentration in Micellar Electrokinetic Chromatography with Enhanced Sensitivity for the Determination of Carbamazepine in Human Serum
Abstract:
A sensitive and simple micellar electrokinetic chromatography (MEKC) method was developed for the determination of antiepileptic drug, carbamazepine (CBZ), using sweeping on-line concentration method with photodiode array detection. Under the optimal conditions, the calbration curve was linear oevr a range of 1.5-40μg·mL-1for CBZ with a correlation clefficient of 0.998.The detection limt(S/N=3:1)of CBZ was 0.10μg·mL-1.The sweeping-MEKC method has been successfully applied to the analysis of CBZ in human serum.
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Key words:
- On-line concentration
- / carbamazepine
- / MEKC
- / sweeping
- / human serum

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