引用本文:
Kamalakar P. Nandre, Jagdish K. Salunke, Jitendra P. Nandre, Vijay S. Patil, Amul U. Borse, Sidhanath V. Bhosale. Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions[J]. Chinese Chemical Letters,
2012, 23(2): 161-164.
doi:
10.1016/j.cclet.2011.11.019
Citation: Kamalakar P. Nandre, Jagdish K. Salunke, Jitendra P. Nandre, Vijay S. Patil, Amul U. Borse, Sidhanath V. Bhosale. Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions[J]. Chinese Chemical Letters, 2012, 23(2): 161-164. doi: 10.1016/j.cclet.2011.11.019
Citation: Kamalakar P. Nandre, Jagdish K. Salunke, Jitendra P. Nandre, Vijay S. Patil, Amul U. Borse, Sidhanath V. Bhosale. Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions[J]. Chinese Chemical Letters, 2012, 23(2): 161-164. doi: 10.1016/j.cclet.2011.11.019
Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions
摘要:
We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).
English
Glycerol mediated synthesis of 5-substituted 1H-tetrazole under catalyst free conditions
Abstract:
We have developed simple, cost effective and environmentally benign protocol for the synthesis of 5-substituted 1H-tetrazoles via [2,3] cycloaddition reaction from organic nitriles and sodium azide in glycerol under catalyst free condition. The corresponding 5-substituted 1H-tetrazoles were obtained with good to excellent yields (68-95%).
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Key words:
- 5-Substituted 1H-tetrazole
- / [2,3] Cycloaddition
- / Nitriles
- / Glycerol
- / Catalyst free
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