An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives

Rahman Hosseinzadeh Yaghoub Sarrafi Nora Aghili

引用本文: Rahman Hosseinzadeh,  Yaghoub Sarrafi,  Nora Aghili. An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives[J]. Chinese Chemical Letters, 2010, 21(10): 1171-1174. doi: 10.1016/j.cclet.2010.06.014 shu
Citation:  Rahman Hosseinzadeh,  Yaghoub Sarrafi,  Nora Aghili. An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives[J]. Chinese Chemical Letters, 2010, 21(10): 1171-1174. doi: 10.1016/j.cclet.2010.06.014 shu

An efficient and mild protocol for the synthesis of unsymmetrical ureas in the absence of catalyst and additives

  • 基金项目:

    Financial support of this work from the Research Council of the University of Mazandaran is gratefully acknowledged.

摘要: A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.

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  • 收稿日期:  2010-02-24
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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