Synthesis of mangiferin derivates and study their potent PTP1B inhibitory activity

• Hong Gang Hu ^a,b, ,
• Ming Juan Wang ^b, ,
• Qing Jie Zhao ^b, ,
• Shi Chong Yu ^b, ,
• Chao Mei Liu ^b, ,
• Qiu Ye Wu ^b,

• a Department of Chemistry, College of Science, Wayne State University, Detroit, MI 48202, United States;

• b Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

• Received Date: 05 June 2007
  
• Fund Project:

  We thank The National Center for Drug Screening (Shanghai,PR China) for supplying data on PTP1B inhibitory activity of the compounds.This work was supported by a grant from Science&Technology Commission of Shanghai Municipality (No.054319909).