引用本文:
Jia Rong Li, Li Jun Zhang, Jin Nan Chen, Xi Quan Yang, Li Jun Wang, Xiao Fan Zhao, Jun Xia Qiu. Synthesis of 2H-3, 1-pyrazolo[3, 4-e]oxazines via a new conversion of Friedl（a）nder reaction[J]. Chinese Chemical Letters,
2007, 18(6): 636-638.
doi:
10.1016/j.cclet.2007.04.015
Citation: Jia Rong Li, Li Jun Zhang, Jin Nan Chen, Xi Quan Yang, Li Jun Wang, Xiao Fan Zhao, Jun Xia Qiu. Synthesis of 2H-3, 1-pyrazolo[3, 4-e]oxazines via a new conversion of Friedl（a）nder reaction[J]. Chinese Chemical Letters, 2007, 18(6): 636-638. doi: 10.1016/j.cclet.2007.04.015
Citation: Jia Rong Li, Li Jun Zhang, Jin Nan Chen, Xi Quan Yang, Li Jun Wang, Xiao Fan Zhao, Jun Xia Qiu. Synthesis of 2H-3, 1-pyrazolo[3, 4-e]oxazines via a new conversion of Friedl（a）nder reaction[J]. Chinese Chemical Letters, 2007, 18(6): 636-638. doi: 10.1016/j.cclet.2007.04.015
Synthesis of 2H-3, 1-pyrazolo[3, 4-e]oxazines via a new conversion of Friedl（a）nder reaction
摘要:
2H-3, 1-Pyrazolo[3, 4-e]oxazines (5a-c) and tacrine analogies (6a-c) were designed and prepared using 5-amino-4-cyanopyrazole (7) and cycloketones (2a-c) as reactants.The study demonstrated that the new conversion existed in the Friedländer reaction of o-aminocyanopyrazole with cycloketones.
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关键词:
- Pyrazole
- / Oxazines
- / Tacrine
- / Cyclocondensation
- / Synthesis
English
Synthesis of 2H-3, 1-pyrazolo[3, 4-e]oxazines via a new conversion of Friedl（a）nder reaction
Abstract:
2H-3, 1-Pyrazolo[3, 4-e]oxazines (5a-c) and tacrine analogies (6a-c) were designed and prepared using 5-amino-4-cyanopyrazole (7) and cycloketones (2a-c) as reactants.The study demonstrated that the new conversion existed in the Friedländer reaction of o-aminocyanopyrazole with cycloketones.
-
Key words:
- Pyrazole
- / Oxazines
- / Tacrine
- / Cyclocondensation
- / Synthesis
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