Diorgano,Dichloro-tin (Ⅳ) Complexes of 4-X-Benzohydroxamic Acid (X=Cl,OCH3):Synthesis,Characterization,Antitumor Activity in Vitro and the Crystal Structure of trans-[Me2Sn(L2)2]

Jing Hua ZHAO Tai Gang LIANG Qing Shan LI Armando J. L. Pombeiro

引用本文: Jing Hua ZHAO,  Tai Gang LIANG,  Qing Shan LI,  Armando J. L. Pombeiro. Diorgano,Dichloro-tin (Ⅳ) Complexes of 4-X-Benzohydroxamic Acid (X=Cl,OCH3):Synthesis,Characterization,Antitumor Activity in Vitro and the Crystal Structure of trans-[Me2Sn(L2)2][J]. Chinese Chemical Letters, 2003, 14(8): 840-843. shu
Citation:  Jing Hua ZHAO,  Tai Gang LIANG,  Qing Shan LI,  Armando J. L. Pombeiro. Diorgano,Dichloro-tin (Ⅳ) Complexes of 4-X-Benzohydroxamic Acid (X=Cl,OCH3):Synthesis,Characterization,Antitumor Activity in Vitro and the Crystal Structure of trans-[Me2Sn(L2)2][J]. Chinese Chemical Letters, 2003, 14(8): 840-843. shu

Diorgano,Dichloro-tin (Ⅳ) Complexes of 4-X-Benzohydroxamic Acid (X=Cl,OCH3):Synthesis,Characterization,Antitumor Activity in Vitro and the Crystal Structure of trans-[Me2Sn(L2)2]

  • 基金项目:

    The financial supports from the National Natural Science Foundation of China (No.39900185), from the State Commission of Science and Technology of China (NO. 96-901-06-38) and from TRAPOYT are gratefully acknowledged.

摘要: A series of diorganotin (Ⅳ) derivatives of R2SnL2 (R=Me, Et, n-Bu, ph or Cl; L=L1 or L2) and their corresponding mixed-ligand complexes R2Sn(L1)(L2) have been prepared and the structure of trans-Me2Sn(L2)2 was characterized by FT-IR, 1H, 13C and 119Sn NMR spectroscopies, MS, elemental analysis, melting points and X-ray diffraction. The structure-activity relationships were discussed.

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  • 收稿日期:  2002-09-02
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