Semisynthesis and Biological Evaluation of Taxayuntin 13-[N-Benzoyl-(2'R,3'S)-3'-phenylisoserinate]

Qin YUE Qi Cheng FANG Xiao Tian LIANG

引用本文: Qin YUE,  Qi Cheng FANG,  Xiao Tian LIANG. Semisynthesis and Biological Evaluation of Taxayuntin 13-[N-Benzoyl-(2'R,3'S)-3'-phenylisoserinate][J]. Chinese Chemical Letters, 1996, 7(10): 886-887. shu
Citation:  Qin YUE,  Qi Cheng FANG,  Xiao Tian LIANG. Semisynthesis and Biological Evaluation of Taxayuntin 13-[N-Benzoyl-(2'R,3'S)-3'-phenylisoserinate][J]. Chinese Chemical Letters, 1996, 7(10): 886-887. shu

Semisynthesis and Biological Evaluation of Taxayuntin 13-[N-Benzoyl-(2'R,3'S)-3'-phenylisoserinate]

  • 基金项目:

    The authors wish to thank Ms. Xiao Hong Lei, Department of Pharmacology of our Institute, for performing cytotoxicity test against KB cell of compounds. Thanks are due to the Department of Instrumental Analysis of our Institute for spectroscopic measurements.

摘要: A novel taxol analog with 5/7/6/4 skeleton, taxayuntin 13-[N-benzoyl-(2'R, 3'S)-3'-phenylisoserinate](8) was semisynthesized with an ED50 of 11.0 μg/ml in cytotoxicity assay against KB cell line.

English

  • 加载中
计量
  • PDF下载量:  2
  • 文章访问数:  936
  • HTML全文浏览量:  10
文章相关
  • 收稿日期:  1996-03-18
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

/

返回文章