Synthesis of 1, 3-cyclic Monoalkyl(acyl)-racglycerothiophosphates of Uridine

Cheng Xiang ZHANG Ru Yu CHEN Chu Chi TANG Huan Ming CHEN

引用本文: Cheng Xiang ZHANG,  Ru Yu CHEN,  Chu Chi TANG,  Huan Ming CHEN. Synthesis of 1, 3-cyclic Monoalkyl(acyl)-racglycerothiophosphates of Uridine[J]. Chinese Chemical Letters, 1996, 7(10): 894-895. shu
Citation:  Cheng Xiang ZHANG,  Ru Yu CHEN,  Chu Chi TANG,  Huan Ming CHEN. Synthesis of 1, 3-cyclic Monoalkyl(acyl)-racglycerothiophosphates of Uridine[J]. Chinese Chemical Letters, 1996, 7(10): 894-895. shu

Synthesis of 1, 3-cyclic Monoalkyl(acyl)-racglycerothiophosphates of Uridine

摘要: New structural phospholipids 1, 3-cyclic monoalkyl(acyl)-rac-glycerothiophosphates of uridine were synthesized.The strategy for the synthesis is using hexaethylphosphorous triamide, activated by a catalytic amount of iodine, as the phosphorylating reagent.Their structures were confirmed by 1HNMR, 31PNMR, IR and elemental analysis.

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  • 收稿日期:  1996-04-22
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