Solid Phase Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazole from Polystyrene-supported Selenium Resin

Wei Ming XU Lu Ling WU Xian HUANG

引用本文: Wei Ming XU,  Lu Ling WU,  Xian HUANG. Solid Phase Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazole from Polystyrene-supported Selenium Resin[J]. Chinese Chemical Letters, 2006, 17(5): 603-605. shu
Citation:  Wei Ming XU,  Lu Ling WU,  Xian HUANG. Solid Phase Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazole from Polystyrene-supported Selenium Resin[J]. Chinese Chemical Letters, 2006, 17(5): 603-605. shu

Solid Phase Synthesis of 1, 4-Disubstituted 1, 2, 3-Triazole from Polystyrene-supported Selenium Resin

  • 基金项目:

    We are grateful to the National Natural Science Foundation of China (No. 20332060) and the Natural Science Foundation of Zhejiang Province (No. Y405407).

摘要: We report here a solid-phase synthesis of 1, 4-disubstituted 1, 2, 3-triazole using polystyrene-supported selenium resin. The resin used here not only works as a simple linker, but also assists the crucial α-alkylation reaction and selenoxide syn-elimination, which ensures the purity of the products.

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  • 收稿日期:  2005-10-24
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