A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media

Robabeh Baharfar Razieh Azimi

引用本文: Robabeh Baharfar,  Razieh Azimi. A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media[J]. Chinese Chemical Letters, 2011, 22(10): 1183-1186. doi: 10.1016/j.cclet.2011.04.020 shu
Citation:  Robabeh Baharfar,  Razieh Azimi. A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media[J]. Chinese Chemical Letters, 2011, 22(10): 1183-1186. doi: 10.1016/j.cclet.2011.04.020 shu

A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media

  • 基金项目:

    Financial support of this work from the Research Council of Mazandran University is gratefully acknowledged.

摘要: A series of pyrido[2, 3-d]pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6-aminothiouracil with α, β-unsaturated carbonyl compounds (aldehyde, ketone and ester) possessing a leaving group on the β position, in H2O under reflux conditions.

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  • 收稿日期:  2011-02-17
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