含芳氧乙酰基和间-三氟甲基苯基的双酰胺化合物的合成及其除草活性

张瀚匀 刘曼赟 严刚 石德清

引用本文: 张瀚匀, 刘曼赟, 严刚, 石德清. 含芳氧乙酰基和间-三氟甲基苯基的双酰胺化合物的合成及其除草活性[J]. 应用化学, 2016, 33(6): 668-676. doi: 10.11944/j.issn.1000-0518.2016.06.150322 shu
Citation:  ZHANG Hanyun, LIU Manyun, YAN Gang, SHI Deqing. Synthesis of Diamides Containing of 2-Aryloxyacetyl and meta-Trifluoromethylphenyl Moieties and Their Herbicidal Activity[J]. Chinese Journal of Applied Chemistry, 2016, 33(6): 668-676. doi: 10.11944/j.issn.1000-0518.2016.06.150322 shu

含芳氧乙酰基和间-三氟甲基苯基的双酰胺化合物的合成及其除草活性

    通讯作者: 石德清,教授;Tel:027-67687958;Fax:027-67862041;E-mail:chshidq@mail.ccnu.edu.cn;研究方向:农药化学、杂环化学、有机合成
  • 基金项目:

    国家自然科学基金(21342004) 

    中央高校自主科研业务费(CCNU14A02007)资助项目 

摘要: 通过组合不同除草作用机制的活性基团,采用芳氧乙酸为酸组分的Ugi四组分反应合成了一系列芳氧乙酰基和间三氟甲基苯基片段的双酰胺化合物3a~3v,采用IR、1H NMR、EI-MS和元素分析等技术手段对其结构进行了表征。温室盆栽测试结果表明,部分目标化合物对油菜、反枝苋、稗草和马唐表现出中等至良好的除草活性,如化合物3r在温室盆栽时,在1.5 kg/ha剂量下,在苗前处理时对反枝苋和马唐显示出100%的抑制活性;在苗后处理时对马唐显示出100%的抑制活性。初步探讨了目标化合物的构效关系。

English

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  • 收稿日期:  2015-09-02
  • 网络出版日期:  2015-11-02
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