引用本文:
Nagnnath D. Kokare, Jaiprkash N. Sangshetti, Devanand B. Shinde. Oxalic acid catalyzed solvent-free one pot synthesis of coumarins[J]. Chinese Chemical Letters,
2007, 18(11): 1309-1312.
doi:
10.1016/j.cclet.2007.09.008
Citation: Nagnnath D. Kokare, Jaiprkash N. Sangshetti, Devanand B. Shinde. Oxalic acid catalyzed solvent-free one pot synthesis of coumarins[J]. Chinese Chemical Letters, 2007, 18(11): 1309-1312. doi: 10.1016/j.cclet.2007.09.008
Citation: Nagnnath D. Kokare, Jaiprkash N. Sangshetti, Devanand B. Shinde. Oxalic acid catalyzed solvent-free one pot synthesis of coumarins[J]. Chinese Chemical Letters, 2007, 18(11): 1309-1312. doi: 10.1016/j.cclet.2007.09.008
Oxalic acid catalyzed solvent-free one pot synthesis of coumarins
摘要:
Oxalic acid was found to be an efficient catalyst for Pechmann condensation, which includes the reaction between phenols and β-keto esters leading to formation of coumarin derivatives. The advantages of present methods are the use of cheap and easy available catalyst, solvent-free reaction conditions, better yields and shorter reaction time.
English
Oxalic acid catalyzed solvent-free one pot synthesis of coumarins
Abstract:
Oxalic acid was found to be an efficient catalyst for Pechmann condensation, which includes the reaction between phenols and β-keto esters leading to formation of coumarin derivatives. The advantages of present methods are the use of cheap and easy available catalyst, solvent-free reaction conditions, better yields and shorter reaction time.
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Key words:
- Coumarins
- / Oxalic acid
- / Solvent-free reaction
- / Pechmann condensation
- / β-Keto esters
- / Phenols
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